Obesity negatively influences joint health by increasing mechanical stress on weight-bearing joints while also increasing chronic inflammation. In excess of body weight, degeneration of cartilage proceeds more rapidly consequently to osteoarthritis, joint pain, and reduced mobility. Also, independent of mechanical stress, adipose tissue secretes inflammatory cytokines and adipokines, which can worsen joint degeneration and compromise musculoskeletal health. Obesity may have detrimental effects on bone density and muscle function, and could further contribute to the risk of encountering joint injury. For individuals with obesity, weight management, physical activity, and anti-inflammatory interventions are important for promoting joint health. Identifying the relationship between obesity and joint health plays a major role in planning preventative and therapeutic strategies to enhance mobility and overall quality of life.
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