The use of anti-obesity devices and wearable technologies is fundamentally changing the field of weight management and metabolic health. These state-of-the-art devices pair biomedical engineering and digital health with data analytics to aid individuals seeking to sustainably manage weight. Devices that are invasive, such as gastric and neuro-stimulation devices, as well as smart wearables that track physical activity, sleep, heart rate, and calories burned, have enabled technology to provide real-time feedback and health-tracking mechanisms. These data-driven tools are used in conjunction with behavioral modification tools to help users make more informed lifestyle choices in a sustainable manner while adhering to weight management programs. The panel will provide a summary of the implications of medical devices, new digital solutions, regulatory issues, and the effectiveness of wearables to combat obesity and metabolic issues.