Terminology such as leaky gut describes gut permeability, which is a breakdown of the intestinal barrier which can allow bacteria, toxins, and food particles to leak into the bloodstream. Consequently, this can induce whole body inflammation and metabolic dysfunction. Research links increased gut permeability to obesity and insulin resistance, as well as metabolic syndrome, and chronic inflammatory conditions. The gut microbiota is a critical component of the barrier structure and is altered by gut bacterial dysbiosis which often makes gut permeability worse. Remedies to achieve gut barrier function include probiotics, and prebiotics, as well as information relating to dietary fibers, anti-inflammatory diets, and behavioral changes. Understanding gut permeability is important, but not limited to: and is ultimately critical in treating obesity, metabolic health, and in one's general well-being overall.
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