Obesity is associated with chronic low-grade inflammation that can impair immune system function. Excess adipose tissue produces pro-inflammatory cytokines, disrupting normal immune responses and increasing susceptibility to infections and autoimmune disorders. Key PointsChronic Inflammation: Adipose tissue releases cytokines like TNF-α and IL-6, promoting systemicinflammation.Impaired Immunity: Obesity affects T-cell and macrophage function, weakening pathogen defense.IncreasedInfection Risk: Higher susceptibility to respiratory infections, influenza, and post-surgical complications.Autoimmune Risk: Chronic inflammation may trigger or exacerbate autoimmune conditions.Management Strategies:Weight reduction through healthy diet and regular physical activity.Anti-inflammatory nutrients (e.g., omega-3 fatty acids, antioxidants) to support immune function.Regular medical check-ups to monitor metabolic and immune health.Addressing obesity not only improves metabolicoutcomes but also enhances immune competence and overall health.