Gut-brain axis is a sophisticated communication system between the gastrointestinal tract and the brain, central to the regulation of appetite, energy balance, and metabolism. Dysfunction in this system can cause overeating and obesity.Hormonal Cues: Gut hormones such as ghrelin, peptide YY, and GLP-1 control hunger and satiety.Neural Signaling: Vagal nerve circuits convey messages between the gut and the brain to modulate appetite.Microbiome Impact: Energy extraction from food and appetite-regulating hormones are affected by gut microbiota.Dysregulation of the gut-brain axis has the potential to cause weight gain and elevated food consumption.High-fiber and prebiotic-rich diet to promote a balanced gut microbiome.Attuned eating habits to synchronize hunger and satiety signals.New therapies that target gut hormones to support weight control.A healthy gut-brain axis is crucial for appetite control and successful obesity prevention and treatment.
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